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Application and preparation method of magnesium hydroxide in medicine

Hebei Messi Biology Co., Ltd. stated that volumetric laxatives are salt preparations that are not easily absorbed by the intestinal wall but are easily soluble in water. After oral administration, a hypertonic salt solution is formed in the intestine, which increases the moisture in the intestinal cavity and expands the volume. , stimulate the intestinal mucosa, causing enhanced intestinal peristalsis and defecation. Drugs include magnesium hydroxide, magnesium sulfate, sodium sulfate, etc.

Magnesium Hydroxide-Pharma Grade

As a laxative, magnesium hydroxide is a salt laxative. After oral administration, it neutralizes with gastric acid and releases magnesium ions. It is not easily absorbed by the intestinal wall but is easily soluble in water. It forms a hypertonic salt solution in the intestine, absorbs a large amount of water and blocks The intestines absorb water, increasing the intestinal volume and increasing intestinal peristalsis to produce defecation. Its advantage in treating constipation is that it does not cause irritation and gently relieves constipation. Domestic single preparations without magnesium hydroxide are on the market. Compound preparations containing magnesium hydroxide on the market include famotidine calcium-magnesium chewable tablets, aluminum-magnesium dimethicone chewable tablets, etc.

Hebei Messi Biology Co., Ltd. stated that the application of magnesium hydroxide in the preparation of drugs to treat constipation in pregnant women can not only effectively relieve and treat constipation in pregnant women, but is also safe and will not affect pregnant women and fetuses. It has the characteristics of accurate efficacy and safe use. . Its pharmaceutical active ingredient is magnesium hydroxide, and the preparation is a tablet or suspension. The invention provides a method for preparing pharmaceutical tablets for treating constipation in pregnant women, which includes the following steps: (1) magnesium hydroxide, diluent, and disintegrant are crushed and sieved respectively, the three are mixed evenly, and the lubricant is sieved; Reserve for later use; (2) Add binder to granulate and dry; (3) Mix the above granules with lubricant and mix evenly; (4) Press into tablets to obtain.v

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